Data Catalog

Positioning of nucleosomes along DNA is an integral regulator of chromatin accessibility and gene expression in diverse cell types. However, the precise nature of how histone demethylases including the histone 3 lysine 4 (H3K4) demethylase, KDM5B, impacts nucleosome positioning around transcriptional start sites (TSS) of active genes is poorly understood. Therefore, to clarify the role for KDM5B in regulating nucleosome organization in ES cells, this study evaluated genome-wide changes in nucleosome positioning in KDM5B-depleted and control ES cells using micrococcal nuclease sequencing (MNase-Seq). These findings demonstrate that depletion of KDM5B leads to altered enrichment of nucleosomes around TSS regions and accessible chromatin regions (DNase I hypersensitive sites).

This study investigates the effect of membership for provincial officials in the Politburo of the single-ruling Chinese Communist Party (CCP) on fiscal resource flows between the central government and provincial governments in reform-era China. This study shows evidence that the provinces overseen by CCP Politburo members tended to remit more budgetary revenues to the center but did not receive larger central budgetary subsidies.

This dataset was generated during a repeated cross-sectional national telephone survey of households, conducted as part of the evaluation of the Robert Wood Johnson Foundation's Urban Health Initiative (UHI). UHI is a long-term effort to improve the health, safety, and well-being of children and youth in five economically distressed cities in the United States: Baltimore, MD, Detroit, MI, Oakland, CA, Philadelphia, PA, and Richmond, VA. The UHI Survey of Adults and Youth (SAY) included a variety of questions, asked of both parents and their 10-18 year old children, regarding children's health, safety, perceptions of neighborhoods and schools, family relations, quality of city services, and other issues. SAY surveyed 3 types of households -- households without children, households with children aged 0-9 years, and households with children aged 10-18 years -- in up to 14 geographic areas, including the 5 UHI program cities, 9 comparison cities demographically similar to the UHI cities, the suburban regions of these cities, the most populous 100 United States cities, and the rest of the country. There were 3 waves of SAY fielded during the course of the UHI project: during the 1998-1999, 2001-2002, and 2004-2005 school years. There is a separate data file for each wave, and each record contains all of the data for a given household.

This data collection documents all cases of military intervention across international boundaries by regular armed forces of independent states in the regions of Europe, the Americas (and Caribbean), Asia and the Pacific, Sub-Saharan Africa, and the Middle East/North Africa. Military interventions are defined operationally in this collection as the movement of regular troops or forces (airborne, seaborne, shelling, etc.) of one country into the territory or territorial waters of another country, or forceful military action by troops already stationed by one country inside another, in the context of some political issue or dispute. The study seeks to identify politically important actions which interpose a state directly into the conflict patterns occurring in another state, and which conceivably involve a breach of the sovereignty of the target state (albeit by invitation in some cases). The collection identifies intervener and target countries and specifies the starting and ending dates of the intervention. A series of potential interests in or motives for intervention are presented, including effects on the target's domestic disputes, foreign or domestic policies, and efforts to protect social factions in the target, to attack rebels in sanctuaries across borders ("hot pursuit"), to protect or enhance economic/resource interests, to protect military or diplomatic facilities, to save lives, or to affect regional power balances and strategic relations. Information is provided on the direction of the intervention, i.e., to support or oppose the target government, to support or oppose opposition groups in the target, or to support or oppose third-party governments or opposition groups. Other variables show the degree of prior intervention, the alliance or treaty relationship between intervener and target, prior colonial status, prior intervention, and measures of intervener and target power size. A series of intensity measures, such as battle-related casualties, is also included. For each type of incursion, by land, sea, or air, an ordinal scale of involvement is presented, ranging from minor engagement such as evacuation, to patrols, acts of intimidation, and actual firing, shelling, or bombing. Finally, contiguity information is provided to indicate both whether intervener and target are geographically contiguous, and whether the intervention was launched from contiguous territory.