Data Catalog

Global signaling profiling in a human model of tumorigenic progression indicates a role for alternative RNA splicing in cellular reprogramming

WSU Dataset

Authors

Joseph A. Caruso

Nicholas Carruthers

Bryan Thibodeau

Timothy J. Geddes

2 more author(s)...

Description

Phosophoproteomic analysis was used to profile cell lines in the MCF-10A lineage of human mammary epithelial cells to determine how human breast cells can be reprogrammed during tumorigenic progression. Data were collected using a LTQ-XL mass spectrometer (Thermo). Phosphopeptides were enriched from cell extracts from 3 independent biological replicates, and each replicate was analyzed as 3 technical replicates for a total of 9 LC/MS/MS runs per cell line.

Subject

Medicine & Health

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