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Global signaling profiling in a human model of tumorigenic progression indicates a role for alternative RNA splicing in cellular reprogramming
WSU Dataset

UID: 74

Description
Phosophoproteomic analysis was used to profile cell lines in the MCF-10A lineage of human mammary epithelial cells to determine how human breast cells can be reprogrammed during tumorigenic progression. Data were collected using a LTQ-XL mass spectrometer (Thermo). Phosphopeptides were enriched from cell extracts from 3 independent biological replicates, and each replicate was analyzed as 3 technical replicates for a total of 9 LC/MS/MS runs per cell line.
Subject Domain
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Grant Support
P30 CA 022453/NIH Cancer Center Support Grant
S10 OD 010700/NIH Shared Instrumentation Grant
P30 ES 020957/NIH Center Grant