Data Catalog

An extensible, scalable informatics platform for traumatic brain injury (TBI) relevant data (including medical imaging, clinical assessment, environmental and behavioral history, etc.) and for all data types (text, numeric, image, time series, etc.). FITBIR is sponsored by the U.S. Army Medical Research and Materiel Command (USAMRMC) and supported by the National Institutes of Health National Institute of Neurological Disorders and Stroke (NINDS) and Center for Information Technology (CIT).

This study examines the whether there is a phylogenetic structure to such episodes of changes in encephalization across mammals. Researchers used phylogenetic techniques to analyze brain mass, body mass and encephalization quotient (EQ) among 630 extant mammalian species. All data on body mass and brain mass of mammals were collected from published literature sources, except for brain masses measured directly from post-mortem specimens the researchers' own collections, and have been entered into a MySQL database.

Multiple cell types can be specified from a single pool of progenitors through the combinatorial activity of transcriptional regulators, which activate distinct developmental programs to establish different cell fates. The zinc finger transcription factor Glass is required for neuronal progenitors in the Drosophila eye imaginal disc to acquire a photoreceptor identity. Glass is also expressed in non-neuronal cone and pigment cells, but its role in these cells is unknown. To examine how Glass activity is affected by the cellular context, the researchers misexpressed it in different tissues. When expressed in neuroblasts of the larval brain or in epithelial cells of the wing disc, Glass activated both a common core set of target genes and distinct gene sets specific to each tissue. In addition to photoreceptor-specific genes, Glass induced markers of cone and pigment cells. Cell type-specific glass mutations generated in cone or pigment cells using somatic CRISPR revealed autonomous developmental defects, and expressing Glass specifically in these cells partially rescued glass mutant phenotypes. Glass thus acts in both neuronal and non-neuronal cells to promote their differentiation into functional components of the eye, suggesting that it is a determinant of organ identity.

This study evaluated advocacy services offered to battered women in Detroit, Michigan, and examined other aspects of coordinated community responses to domestic violence by focusing on women named as victims in police reports. Advocacy was defined as those services provided to support victims during the legal process or to enhance their safety. For the Preliminary Complaint Reports Data (Part 1), a random sample of preliminary complaint reports (PCRs), completed by police officers after they responded to domestic violence calls, were gathered, resulting in a sample of 1,057 incidents and victims. For Victim Advocacy Contact Data (Part 2), researchers obtained data from advocates' files about the services they provided to the 1,057 victims. For Case Disposition Data (Part 3), researchers conducted a computer search to determine the outcomes of the cases. They looked up each perpetrator from the list of 1,057 incidents, and determined whether there was a warrant for the focal incident, whether it turned into a prosecution, and the outcome. The Initial Victim Interview (Part 4) and Follow-Up Victim Interview Data (Part 5) were conducted from April 1998 to July 1999. During the same period that researchers were completing the second interviews, they also interviewed 23 women (Victim Comparison Group Interview Data, Part 6) from the list of 1,057 whom they had been unable to reach during the first interviews. They compared these 23 women to the 63 who had second interviews to determine if there were any differences in use of services, or views toward or participation in prosecution. Variables in Part 1 focus on whether alcohol and abuse were involved, previous incidents, the suspect's psychological aggressions and physical assaults, if a weapon was used, if the victim was hurt, if property was damaged, if the victim sought medical attention, and the severity of physical abuse or injury. Variables in Part 2 provide information on the role of the advocate, methods of contact, types of referrals made, and services provided. Variables in Part 3 include the type of charge, outcome of resolved case, why the case was dismissed, if applicable, and if the suspect was sentenced to probation, costs, confinement, no contact with the victim, a batterer program, or community service. [...]