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Preeclampsia, a frequent complication of pregnancy that affects 5%-8% of all gestations, is a leading cause of maternal, and perinatal morbidity and mortality. Over the last decade, it has become clear that preeclampsia is not a single disorder but a syndrome with many etiologies, such as abnormal placentation, utero-placental ischemia, vascular disorders of the placenta, insulin resistance, systemic maternal inflammation, endothelial dysfunction, and imbalance of angiogenic and anti-angiogenic proteins. A case-control longitudinal study was conducted, including 90 patients with normal pregnancies and 76 patients with late-onset preeclampsia (diagnosed at ≥34 weeks of gestation). Maternal plasma samples were collected throughout gestation (normal pregnancy: 2–6 samples per patient, median of 2; late-onset preeclampsia: 2–6, median of 5). The abundance of 1,125 proteins was measured using an aptamers-based proteomics technique. Protein abundance in normal pregnancies was modeled using linear mixed-effects models to estimate mean abundance as a function of gestational age. Data was then expressed as multiples of-the-mean (MoM) values in normal pregnancies. Multi-marker prediction models were built using data from one of five gestational age intervals.
The Pediatric Participant Use Data File (PUF) is a Health Insurance Portability and Accountability Act (HIPAA)-compliant data file containing cases submitted to the American College of Surgeons National Surgical Quality Improvement Program Pediatric® (ACS NSQIP Pediatric®). The PUF contains patient-level, aggregate data and does not identify hospitals, health care providers, or patients. The ACS NSQIP Pediatric collects data on approximately 120 variables, including preoperative risk factors, intraoperative variables, and 30-day postoperative mortality and morbidity outcomes for patients undergoing major surgical procedures in both the inpatient and outpatient setting. The intended purpose of this file is to provide researchers at participating sites with a data resource they can use to investigate and advance the quality of care delivered to the surgical patient through the analysis of cases captured by ACS NSQIP Pediatric. Additional procedure-specific PUFs are available for appendectomy, spinal fusion, and cerebrospinal fluid shunt.
This data was collected as part of an expedition to the Pacific Ocean and Atlantic Oceans to map and study the distribution of trace elements and isotopes as part of the International GEOTRACES Program (a program which aims to improve the understanding of biogeochemical cycles and large-scale distribution of trace elements and their isotopes in the marine environment). hundreds of samples were collected, processed, and analyzed along the two transects: EPZT in the Eastern Pacific between Peru and Tahiti, and GEOVIDE in the North Atlantic and Arctic between Portugal and Newfoundland, Canada. Along both transects, samples were collected at specific stations and the activity of the radionuclides was measured on both particle (small and large) and in the water column.
The City of Detroit Open Data Portal allows access to datasets, maps, charts, and files and documents on City of Detroit government operations and programs, public safety (Detroit Police Department, Detroit Fire Department, and Detroit Department of Homeland Security), property and parcels, schools and educational institutions, transportation, public health, and permits.
The National Survey on Drug Use and Health provides up-to-date information on tobacco, alcohol, and drug use, mental health and other health-related issues in the United States. NSDUH began in 1971 and is conducted every year in all 50 states and the District of Columbia. Information from NSDUH is used to support prevention and treatment programs, monitor substance use trends, estimate the need for treatment and inform public health policy.
From the MDHHS website: "The MiTracking Program gathers existing Michigan-specific environmental and health data and provides them in one online location. These data can be easily queried on the MiTracking data portal. Results are provided in tables, charts, and maps that can be downloaded, saved, and printed. The data provided by the MiTracking program can create greater awareness of environmental health concerns, and inform public health actions and programs."
An extensible, scalable informatics platform for traumatic brain injury (TBI) relevant data (including medical imaging, clinical assessment, environmental and behavioral history, etc.) and for all data types (text, numeric, image, time series, etc.). FITBIR is sponsored by the U.S. Army Medical Research and Materiel Command (USAMRMC) and supported by the National Institutes of Health National Institute of Neurological Disorders and Stroke (NINDS) and Center for Information Technology (CIT).
This study was designed to provide information on attitudes and opinions regarding a number of issues of importance to Black Americans. Topics included the performance of President Bill Clinton, the economic condition of Black Americans, and what respondents thought ought to be done to improve the condition of Black people. Questions regarding Black women and their role in the Black community were also asked. In addition, the role and extent of religion in Black politics was investigated. Respondents also provided information about their political self-identification and their community and political involvement, as well as their feelings toward various political leaders, political groups, and national policies. Demographic information on respondents includes sex, age, education, marital status, income, and occupation and industry.
Recent studies suggest the necessity of understanding the interactive effects of predation and productivity on species coexistence and prey diversity. Models predict that coexistence of prey species with different competitive abilities can be achieved if inferior resource competitors are less susceptible to predation and if productivity and/or predation pressure are at intermediate levels. Hence, predator effects on prey diversity are predicted to be highly context dependent: enhancing diversity from low to intermediate levels of productivity or predation and reducing diversity of prey at high levels of productivity or predation. While several studies have examined the interactive effects of herbivory and productivity on primary producer diversity, experimental studies of such effects in predator-prey systems are rare. We tested these predictions using an aquatic field mesocosm experiment in which initial density of the zooplankton predator Notonecta undulata and productivity were manipulated to test their interactive effects on diversity of seven zooplankton, cladoceran species that were common in surrounding ponds. Two productivity levels were imposed via phosphorus enrichment at levels comparable to low and intermediate levels found within neighboring natural ponds. We used open systems to allow for natural dispersal and behaviorally-mediated numerical responses by the flight-capable predator. Effects of predators on zooplankton diversity depended on productivity level. At low and high productivity, prey species richness declined while at high productivity it showed a unimodal relationship with increasing the predator density. Effects of treatments were weaker when using Pielou's evenness index or the inverse Simpson index as measures of prey diversity. Our findings are generally consistent with model predictions in which predators can facilitate prey coexistence and diversity at intermediate levels of productivity and predation intensity. Our work also shows that the functional form of the relationship between prey diversity and predation intensity can be complex and highly dependent on environmental context.
The goal of this study was to investigate the influence of female parents on the sexual and contraceptive behavior of teenage daughters. The strategy for doing so was to examine patterns of communication about sex roles and sexual behavior between mothers and daughters in different types of families and to measure the impact of varying communication patterns on the sexual and contraceptive knowledge and behavior of daughters. Demographic, attitudinal, and behavioral data were collected from both mothers and daughters in Detroit, Michigan, in separate but simultaneous face-to-face interviews.