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Papillary carcinomas constitute 1–2% of breast carcinomas in women. Solid papillary carcinoma (SPC) is a rare variant of papillary carcinoma with unique pathological morphology and biological behavior and has recently been classified as a new category of breast papillary carcinoma by the World Health Organization (2012), differentiating it from the previous classification as a type of intraductal papillary carcinoma. This retrospective study included four pathology-confirmed in situ SPC patients. Conventional MRI, diffusion weighted imaging (DWI), and magnetic resonance spectroscopy (MRS) were performed with a 1.5 T whole-body MR scanner before surgical operation. The following characteristics of each lesion were recorded: signal intensity on T2WI/STIR and T1FSPGR, morphology, maximum lesion size, and time intensity curve (TIC) on dynamic contrast enhancement MRI (DCE-MRI), apparent diffusion coefficient (ADC) value from DWI, and Cho peak from MRS.
The objective of this phase II/III randomized clinical trial is to evaluate the efficacy of vitamin D therapy versus placebo in vitamin D-deficient African-Americans with hypertension, including investigating the relationship between vitamin D and cardiac damage (as identified on cardiac magnetic resonance imaging) in a vitamin D-deficient hypertensive patients without prior history of heart disease. Data include cardiac MRI and echocardiography data, lab results (e.g., vitamin D, CBC), and patient characteristics (e.g., vital signs, demographics, health insurance, education level, household income, hypertension drug and vitamin D treatment adherence, dietary intake, sun exposure).