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Basic clinical measures for all patients seen at Detroit Medical Center emergency departments, including hospital ID, reason for visit, age, gender, height, weight, systolic blood pressure, diastolic blood pressure, and patient ZIP code.
Prospective registry and biorepository of consecutive patients who present to emergency departments in the Detroit Medical Center with (1) an established history of hypertension (HTN) or (2) elevated blood pressure with no history of HTN. Patients are surveyed using validated Survey instruments including the SF-12 Health Survey, Patient Activation Measure short form (PAM-13), Berlin Obstructive Sleep Apnea Scale, Social Support Questionnaire short form (SSQ-6), Perceived Stress Scale (PSS-14), MacArthur Scale of Subjective Social Status, Six-Item Cognitive Impairment Test (6-CIT), and Brief Coping Orientation to Problems Experienced (Brief COPE). Biological specimens are obtained from consenting individuals. Other collected data include patient demographics, vital signs, physical examination, basic medical history, medications, electrocardiography, x-ray, and lab results.
The objective of this phase II/III randomized clinical trial is to evaluate the efficacy of vitamin D therapy versus placebo in vitamin D-deficient African-Americans with hypertension, including investigating the relationship between vitamin D and cardiac damage (as identified on cardiac magnetic resonance imaging) in a vitamin D-deficient hypertensive patients without prior history of heart disease. Data include cardiac MRI and echocardiography data, lab results (e.g., vitamin D, CBC), and patient characteristics (e.g., vital signs, demographics, health insurance, education level, household income, hypertension drug and vitamin D treatment adherence, dietary intake, sun exposure).