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It has long been thought that biomedical doctoral students pursue careers primarily as tenure-track/tenured faculty at research institutions. Recent reports showed, however, that the majority of biomedical doctoral alumni engage in a variety of careers. Wayne State University (WSU) undertook a project to understand the career trajectories of its biomedical doctoral alumni to create programs to better prepare its students for careers in multiple pathways. Data were collected on career outcomes of WSU's biomedical doctoral alumni who graduated in a 15-year period from 1999-2014. Careers were classified into three tiers by Employment Sector, Career Types and Job Functions and career paths were examined by alumni gender, race, U.S. citizenship status, and association with certain academic characteristics. Several statistically significant differences in career paths among all demographics were found.
Müller glia in the zebrafish retina respond to retinal damage by re-entering the cell cycle, which generates large numbers of retinal progenitors that ultimately replace the lost neurons. In this study, researchers compared the regenerative outcomes of adult zebrafish exposed to one round of phototoxic treatment with adult zebrafish exposed to six consecutive rounds of phototoxic treatment. It was observed that Müller glia continued to re-enter the cell cycle to produce clusters of retinal progenitors in zebrafish exposed to multiple rounds of phototoxic light.
The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a multi-center epidemiologic study in Hispanic/Latino populations to assess the role of acculturation in the prevalence and development of disease, and to identify factors playing a protective or harmful role in the health of Hispanics/Latinos. The target population of 16,000 persons of Hispanic/Latino origin, specifically Cuban, Puerto Rican, Dominican, Mexican, and Central/South American, were recruited through four Field Centers in Miami, San Diego, Chicago and the Bronx area of New York. During 2008-2011 study participants aged 18-74 years underwent an extensive clinic exam and assessments to determine baseline risk factors. Annual follow-up interviews are conducted to determine health outcomes of interest. During the 2014-2017 second clinic visit (Visit 2) participants were re-examined to again collect data predictive of various health outcomes of interest. In addition, a comprehensive reproductive history of women of childbearing age was assessed. The third clinic operations aka "visit" began January 2020 and will conclude in early 2023. HCHS-SOL provides the prevalence of 5 major, readily measured biomedical CVD risk factors (high serum cholesterol and blood pressure levels, obesity, hyperglycemia/diabetes, cigarette smoking), adverse CVD risk profiles (combinations of CVD risk factors), and CVD (coronary heart disease [CHD] and stroke) among US Hispanic/Latino adults of diverse backgrounds.
The Pediatric Participant Use Data File (PUF) is a Health Insurance Portability and Accountability Act (HIPAA)-compliant data file containing cases submitted to the American College of Surgeons National Surgical Quality Improvement Program Pediatric® (ACS NSQIP Pediatric®). The PUF contains patient-level, aggregate data and does not identify hospitals, health care providers, or patients. The ACS NSQIP Pediatric collects data on approximately 120 variables, including preoperative risk factors, intraoperative variables, and 30-day postoperative mortality and morbidity outcomes for patients undergoing major surgical procedures in both the inpatient and outpatient setting. The intended purpose of this file is to provide researchers at participating sites with a data resource they can use to investigate and advance the quality of care delivered to the surgical patient through the analysis of cases captured by ACS NSQIP Pediatric. Additional procedure-specific PUFs are available for appendectomy, spinal fusion, and cerebrospinal fluid shunt.
The Maternal Lifestyle Study (MLS) was the largest of the NIH longitudinal studies of children with prenatal cocaine exposure (PCE). MLS was a longitudinal multi-site observational study of the long-term effects of in-utero exposure to cocaine on child development. MLS was conducted at four geographically diverse, collaborating university centers (Wayne State University, University of Tennessee at Memphis, University of Miami, and Brown University). Participants were identified during the newborn period while in the hospital. The MLS began enrollment of a longitudinal birth cohort of 1,388 infant/mother dyads in 1993. Subjects in the follow-up were seen from 1 month of age through 16 years of age. The overall purpose of the study was to investigate the effects of drug use during pregnancy on acute neonatal events and long-term physical health, social, behavioral and neurodevelopmental outcomes.
This study evaluated advocacy services offered to battered women in Detroit, Michigan, and examined other aspects of coordinated community responses to domestic violence by focusing on women named as victims in police reports. Advocacy was defined as those services provided to support victims during the legal process or to enhance their safety. For the Preliminary Complaint Reports Data (Part 1), a random sample of preliminary complaint reports (PCRs), completed by police officers after they responded to domestic violence calls, were gathered, resulting in a sample of 1,057 incidents and victims. For Victim Advocacy Contact Data (Part 2), researchers obtained data from advocates' files about the services they provided to the 1,057 victims. For Case Disposition Data (Part 3), researchers conducted a computer search to determine the outcomes of the cases. They looked up each perpetrator from the list of 1,057 incidents, and determined whether there was a warrant for the focal incident, whether it turned into a prosecution, and the outcome. The Initial Victim Interview (Part 4) and Follow-Up Victim Interview Data (Part 5) were conducted from April 1998 to July 1999. During the same period that researchers were completing the second interviews, they also interviewed 23 women (Victim Comparison Group Interview Data, Part 6) from the list of 1,057 whom they had been unable to reach during the first interviews. They compared these 23 women to the 63 who had second interviews to determine if there were any differences in use of services, or views toward or participation in prosecution. Variables in Part 1 focus on whether alcohol and abuse were involved, previous incidents, the suspect's psychological aggressions and physical assaults, if a weapon was used, if the victim was hurt, if property was damaged, if the victim sought medical attention, and the severity of physical abuse or injury. Variables in Part 2 provide information on the role of the advocate, methods of contact, types of referrals made, and services provided. Variables in Part 3 include the type of charge, outcome of resolved case, why the case was dismissed, if applicable, and if the suspect was sentenced to probation, costs, confinement, no contact with the victim, a batterer program, or community service. [...]