Data Catalog

This data was collected as part of an expedition to the Pacific Ocean to map and study the distribution of trace elements and isotopes as part of the International GEOTRACES Program (a program which aims to improve the understanding of biogeochemical cycles and large-scale distribution of trace elements and their isotopes in the marine environment). 135 seawater samples were collected and analyzed from 6 super stations from east to west along a transect from Peru to Tahiti.

This data was collected as part of an expedition to the Pacific Ocean and Atlantic Oceans to map and study the distribution of trace elements and isotopes as part of the International GEOTRACES Program (a program which aims to improve the understanding of biogeochemical cycles and large-scale distribution of trace elements and their isotopes in the marine environment). hundreds of samples were collected, processed, and analyzed along the two transects: EPZT in the Eastern Pacific between Peru and Tahiti, and GEOVIDE in the North Atlantic and Arctic between Portugal and Newfoundland, Canada. Along both transects, samples were collected at specific stations and the activity of the radionuclides was measured on both particle (small and large) and in the water column.

B-cells play a pivotal role in several autoimmune diseases, including patients with immune-mediated neurological disorders (PIMND), such as neuromyelitis optica (NMO), multiple sclerosis (MS), and myasthenia gravis (MG). Targeting B-cells has been an effective approach in ameliorating both central and peripheral autoimmune diseases. However, there is a paucity of literature on the safety of continuous B-cell depletion over a long period of time. The aim of this study was to examine the long-term safety, incidence of infections, and malignancies in subjects receiving continuous therapy with a B-cell depleting agent rituximab over at least 3 years or longer. This was a retrospective study involving PIMND who received continuous cycles of rituximab infusions every 6 to 9 months for up to 7 years. The incidence of infection related adverse events (AE), serious adverse events (SAE), and malignancies were observed.